Mediterranean Diet Linked to Improved IVF Success, Review Finds

In the realm of fertility treatments, particularly in vitro fertilization (IVF), the impact of diet and supplements on success rates has been a subject of interest.

A recent review, published in Reproductive Biomedicine Online (RBMO), examined 27 studies to explore the influence of nutritional therapies on IVF outcomes. The findings suggest that adhering to a Mediterranean diet could enhance the likelihood of successful IVF. Additionally, certain supplements, including DHEA, COQ-10, melatonin, myo-inositol, and omega-3 free fatty acids, were implicated in improving IVF success in specific scenarios.

Navigating the Complexity of IVF Success Factors

In vitro fertilization involves fertilizing an egg outside the body and implanting the fertilized egg into the uterus, offering hope for couples facing challenges in conceiving. The success of IVF depends on various factors, such as ovarian reserve, ovarian stimulation, fertilization, embryo development, and implantation. For individuals undergoing IVF, who often already contend with fertility struggles, each step in the process is crucial, and optimizing outcomes becomes paramount.

Dr. Albrar Al-Shaer, Ph.D., from Nourish Women Nutrition, LLC, emphasizes the intricate nature of IVF success, where multiple factors need optimization. She notes that supplements can be a valuable strategy to enhance fertility and conception outcomes in the context of IVF.

Insights from the Comprehensive Review

The systematic review analyzed studies conducted between January 2015 and May 2023, focusing on nutritional supplements and their impact on IVF outcomes. The study considered DHEA and COQ-10 supplements beneficial for women undergoing ovarian stimulation, a crucial step in IVF. The findings underscored that taking these supplements before initiating the IVF cycle led to improved outcomes compared to control therapies.

Professor Roger Hart, the study author, emphasized the potential benefits of CoQ10 alone, particularly for older women, those with a poor response to ovarian stimulation, or those with cycles characterized by poor embryonic development. Omega-3 free fatty acids and melatonin were also identified as supplements that may benefit certain IVF outcomes, with specific dosages and patient criteria yet to be determined.

The Role of the Mediterranean Diet in IVF Success

In addition to supplements, the review highlighted the positive impact of adopting a Mediterranean diet on IVF success. The principles of this diet include:

1. Abundance of Vegetables, Legumes, and Fruits: Incorporating a variety of plant-based foods rich in nutrients.
2. Whole Grains: Choosing whole wheat bread and pasta over refined alternatives.
3. Lean Proteins: Opting for fish and poultry more frequently than red meat.
4. Healthy Fats: Embracing plant-based fats from olive oil, avocados, nuts, and seeds.
5. Limiting Processed Foods: Reducing the intake of highly processed and refined foods.

Professor Roger Hart suggests that adopting a Mediterranean diet, with its emphasis on nutrient-rich foods, offers a slightly greater chance of IVF success compared to a traditional high-fat and high-carbohydrate Western diet.

Considerations and Future Research

While the review provides valuable insights, it acknowledges certain limitations. Future research is essential to confirm findings, determine treatment effects, establish appropriate supplement dosages, and identify specific patient subgroups benefiting from these interventions. As individuals embark on the complex and personal journey of IVF, communication with specialists about nutrition, supplements, and tailored strategies remains crucial.

As research in this field progresses, the goal is to offer evidence-based guidance, addressing the unique needs of individuals undergoing IVF and contributing to improved fertility outcomes. The study underscores the intersection of science and lifestyle choices in the realm of fertility, opening avenues for further exploration and support for those navigating the challenges of assisted reproductive technologies.

Reference: IVF: Mediterranean diet, some supplements may increase success rate (medicalnewstoday.com)